JWH-073 ,化学名N -正丁基-3-(1-萘甲酰基)吲哚 ,分子式C23 H21 NO ,属于萘 甲酰基吲哚 类JWH系列大麻素 ,是大麻素受体 CB1 和CB2 的全激动剂 [3] ,由约翰·威廉·霍夫曼 小组合成[4] 。
参考文献 [ 编辑 ]
^ Grozījumi Ministru kabineta 2005.gada 8.novembra noteikumos Nr.847 "Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem" . Legal Acts of the Republic of Latvia. [2024-01-29 ] . (原始内容存档 于2010-09-14) (Latvian) .
^ Anvisa . RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] . Diário Oficial da União . 2023-07-24 (2023-07-25) [2023-08-27 ] . (原始内容存档 于2023-08-27) (巴西葡萄牙语) .
^ Lisa K. Brents, Anna Gallus-Zawada, Anna Radominska-Pandya, Tamara Vasiljevik, Thomas E Prisinzano, William E Fantegrossi, Jeffery H Moran, Paul L Prather. Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity . Biochemical Pharmacology. 2012, 83 (7): 952–961 [2024-01-29 ] . PMID 22266354 . doi:10.1016/j.bcp.2012.01.004 . hdl:1808/22684 . (原始内容存档 于2023-10-31). JWH-073 displays equivalent efficacy to that of the CB1R full agonist CP-55,940
^ Aung MM, Griffin G, Huffman JW, Wu M, Keel C, Yang B, Showalter VM, Abood ME, Martin BR. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 )receptor binding. Drug Alcohol Depend. August 2000, 60 (2): 133–40. PMID 10940540 . doi:10.1016/S0376-8716(99)00152-0 .
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